Synthesis of substituted pyrazole-4-carbaldehyde and investigation of advanced stage reactions

Pyrazole compound is a five membered of heterocyclic molecule with two neighboring nitrogen atoms connected with three carbon atoms. İt forms an important class of heterocyclic molecules. Recently many pyrazole compound with different structures are designed because of its important pharmacologic, agricultural and biological activities. Therefore, the investigation of heterocyclic compound's synthesis and biological activities gained importance. Acridine also is a synthetic molecule used in dye and some valuable drug synthesis without having a natural ring system. In this study, it is aimed to synthesize and characterize newly designed pyrazole-acridine compounds having different biological activity potentials. Therefore, in the first step we synthesized our compounds of 1-(benzo [d] thiazol-2-yl)-3-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde according to literature. New pyrazole-acridine-sulfonamide derivatives containing different biologically active groups are synthesized by ringing by -diketone (5,5-dimethylcyclohexane-1,3-dione) and different aromatic amines. The synthesized compound structures emerged by using FT-IR, 1H-NMR, 13C-NMR and mass spectrum data.