A retrospective study of stone analysis, metabolic evaluation results and their effect on metaflaxy in Tekirdag province

In our study; we aimed to present the results of stone analysis and metabolic evaluation in Tekirdag province, where is an endemic region in terms of stones, and to determine the demographic and personal characteristics and relationships of patients with these, and to reveal their effects on metaphylaxis. For this purpose, the data of 312 patients with urinary system stone disease who applied to our clinic between August 2018 and January 2021 were analyzed. Stone analysis was performed to these patients by using the spectroscopic method. The metabolic evaluation was performed in 24-hour urine and serum simultaneously to 156 of the patients with stone analysis. Age, gender, BMI of the patients, and the centers where the patients reside; the side distribution, localization, stone densities (HU), volumes, and 24-hour urine and serum parameters of the patients were evaluated. Stones in different localizations in the urinary system were also analyzed separately. The stone disease was predominantly in males, on the left side, in multiple locations in the urinary system, frequently single, with sterile urine culture, and mostly in patients residing in the city centers. The most frequently detected type of stone is calcium oxalate; the least common type of stone was xanthine. The highest mean HU is in calcium oxalate stones and the lowest in uric acid+ammonium urate stones. As the calcium content increases, the HU of the stone increases. The stone type with the highest mean stone volume is cystine and the lowest is xanthine. The most common stone patient age is 50-59; it is rarely seen under the age of 18. Hypercalciuria is the most common and hypercystinuria is the least common parameter; the most commonly hyperuricemia and least hypercalcemia were observed in plasma. Potassium citrate was used most frequently for metaphylaxis. 76 After all; the stone diversity and predisposing metabolic disorders in our city were examined and their clinical implications were evaluated. More attention and time should be devoted to metabolic evaluation. Key Words: Stone analysis, metabolic evaluation, metaphylaxis