Determination of parathion with Tis2/Go nanocomposite based nanosensors

Objective: This study was conducted to determine the pesticide parathion using TiS₂/GO Nanocomposite-Based Nanosensors. Material and Methods: In this study, parathion detection was performed via an electrochemical method using a TiS₂/GO nanocomposite-modified electrode, followed by optimization, characterization, and evaluation of analytical performance Results: : The synthesized TiS₂/GO-coated biosensors were morphologically characterized using scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX), while their electrochemical behavior was evaluated through differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS) measurements. For the detection of the widely used pesticide Parathion, screen-printed electrodes (SPEs) were modified with a composite of TiS₂/GO and 5% Nafion™. Optimization studies indicated that the maximum current response (153.425 µA) was obtained at pH 7.0, with acceptable reproducibility (relative standard deviation, RSD = 6.864%). A linear relationship between current response and Parathion concentration was established over a range of 10⁻9 to 10⁻⁴ M. Furthermore, repeatability tests conducted at 10⁻⁵ M Parathion demonstrated high precision, yielding a low RSD of 1.46% Conclusion: This thesis study presents the electrochemical determination of parathion using TiS₂/GO nanocomposite-modified screen-printed electrodes (SPEs). The developed electrochemical method offers a viable alternative to conventional analytical techniques, demonstrating its potential as a complementary approach for parathion detection. Key Words: Amperometry, Graphene oxide (GO), Nanocomposite, Parathion, Pesticide, Sensor, Titanium disulfide (TiS₂)