The effect of surface modifications for the aim of decreasing bacterial adhesion on titanium implants

Surface modification of titanium surfaces offers a potential solution to reduce the risk of bacterial adhesion and extend the lifespan of implants. This study aimed to explore the impact of different surface patterns on bacterial adhesion and develop an appropriate pattern to minimize such adhesion on titanium plate surfaces. The honeycomb pattern was specially selected for its various applications in the field of biomedical engineering and the four distinct pattern groups were generated, including Plain, Line Type 1, Line Type 2, and Honeycomb Patterns. Preliminary experiments were conducted to compare Line Type 1 and Line Type 2 groups. Statistical analysis revealed no significant difference in bacterial colony-forming units (CFU) values, and based on the results, Plain, Line Type 1, and Honeycomb pattern groups were further evaluated. Although a minor difference in mean CFU values was observed in the honeycomb group compared to other groups, the difference was not significant enough to support the adoption of honeycomb patterns as a definitive solution for effectively minimizing bacterial adhesion on titanium and its alloys surfaces. These findings provide useful insights into the selection and effectiveness of surface patterns in reducing bacterial adhesion on titanium plates. Key Words: Pattern, Titanium Plates, Bacterial Adhesion