The synthesis of new amides and n- aroyl-n'-(alkyl/aryl) thioureas and investigation of their hydrogen interaction with divers anions

In this research, new thioureas (A-D) and amides (E-F) were synthesized using p-nitrobenzoylchloride and o- phthaloyldichloride with 5-chloropyridin-2-amine, 5-bromopyridin-2-amine, 4-amino-2,5-dimethyl-1-phenyl-1H-pyrazol-3(2H)-one and 4-nitroaniline. The structure of the new compounds were confirmed by FT-IR, 1H-NMR, 13C-NMR and MS spectrum data. Interactions of these thioureas with anions (Cl-, Br-, F-, I-, OH-, H2PO4-, AcO- and CN-) were investigated by UV-vis spectrophotometric methods. Color changes observed were photographed. UV-vis spectrophotometric titration were also carried out by adding a standart solution of tetrabutiylammonium fluoride in DMSO to a solution thioureas and hydrogen-fluoride binding constants (logK) were calculated from the titration profile.