Synthesis of some derivatives of 4-benzoyl-1-(3-nitrophenyl)-5-phenyl-n-(4-sulfamoylphenyl)-1h-pyrazole-3-carboxamide and illumination of their structures

Substituted pyrazoles exhibit a wide variety of biological and pharmacological activities and they have a broad application area both in medical and agrochemical industries. Therefore, methods developed for synthesizing these compounds are getting more importance.In this study, which is the starting compound 4-benzoyl-1-(3-nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid the reaction was amide formation with sulfonamides.On the other hand, primary aromatic amine group, put on 0 °C by reaction with NaNO2 and HCl was converted to salt diazonyum. Diazonyum of compounds, the active hydrogen containing various 1,3-dicarbonyl compounds and ß-napthol with clenching new sulfonamides derivatives were obtained as a result.Structures of resultant compounds examined with IR, 1H-NMR, 13C-NMR and MASS spectroscopy methods