Evaluation of radiofrquency and microwave ablation procedures' efficiency in the treatment of malignant lung tumours

This study designed retrospective to evaluate the efficiency of radiofrequency and microwave ablation of oligometastatic disease of lung and primary lung tumours. For this purpose, we analysed total survival, disease free survival and local reccurence parameters and beside it determined the complications of these procedures, compare each other by means of side effects. Local tumour progression, total survival, disease free survival and complication ratios are evaluated seperately for radiofrequency and microwave ablation compared with each other. Findings analyzed with SPSS software. Parametric and non-parametic tests are used for calculations such as Independent Samples Test, Two-Sample KolmogorovSmirnov Test, Chi-Square test and for the survival analyses Kaplan-Meier method. In this study, we included 26 patients with 40 lung tumours who has been under radiofrequency and microwave ablation procedures between October 2008 – May 2015 in the Başkent University Medical Faculty, Ankara Hospital, Radiology department, Interventional Radiology section. On the purpose of calculate the total and disease free survival, determine local tumour progression rates and complicatons of the procedures. Files of the patients are examined retrospectively. 6 women and 20 men of 26 patients were aged between 23-77 (58,78±11,24). 14 tumours were treated with microwave ablation and 26 tumours were treated with radiofrequency ablation. Tumour diameters were between 5 mm – 45 mm ( 16,25 ±10,65 mm) and 6 of 40 were primary lung cancers and 34 of 40 were metastases of other cancers which were dominantly primary colorectal cancers. Median follow-up was 36,18±21,42 month. Just 1 patient had stopped follow-up and therefore we excluded him from the study. 8 patients died between this perid and 17 patients still in follow-up currently. During the ablation procedures 4 major complications occured which are necessitate curative atempt. 3 of 4 was pneumothorax and 1 of 4 was hemothorax iv Radiofrequency and microwave ablation procedures are very effective for the treatment of the lung tumours by controlling the local progression, increasing the total and disease free survival of patients. Under favour of all these benefits, with low complicaton rates and lesser hospitalisation period, these procedures get more place in the daily practice of the treatment of lung tumours day by day. Key Words: Lung cancer, lung metastases, thermal ablation, radiofrequency ablation, microwave ablation