Master'sOpen Access

Synthesis of ellipticine derivatives which show antitumor activity and spectroscopic studies

2007
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Advisor: Doç. Dr. M. Yavuz Ergün

Abstract (EN)

In this study, 11-Methyl-6H-pyrido [4,3-b] carbazole (5-Demethyl Ellipticine) , which is a pyrido carbazole derivative , was synthesized via D type synthesis plan. So, 4-methyl-1,2,3,4-tetrahydro-9H-carbazole-3-carboxylic acid which was synthesized earlier was used as a starting compound. The ellipticine derivative was synthesized by consecutive synthesis steps to form the forth cycle of this compound. Synthesized compounds were purified by using chromatographic methods and their structures were identified by using IR, 1H NMR and mass spectra.

Author

Sibel Gülle

How to Cite

Sibel Gülle (Master Thesis). Synthesis of ellipticine derivatives which show antitumor activity and spectroscopic studies, 2007, Dokuz Eylül University.

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