MIP based qcm sensor for real time detection of Cu(II) ions

Within the scope of the presented thesis, it was aimed to prepare gravimetric nanosensors for the determination of Cu(II) ions in real time by combining the high sensitivity and selectivity properties of nanotechnology with the molecular printing method without expensive devices and the necessity of laboratory conditions. Thus, poly(hydroxyethyl-methacrylate) (pHEMA) based Cu(II) ion imprinted [Cu(II)-MIP] nanoparticles were prepared in the size range of 100 nm. These Cu(II)-MIP nanoparticles were characterized in structure by the methods, such as scanning electron microscopy (SEM), zeta size distribution analysis and FTIR spectroscopy. Cu(II)-MIP nanoparticles were then adapted to QCM nanosensor for the real time detection of Cu(II) ions in aqueous solutions. The parameters of initial ion concentration and selectivity were investigated to obtain the optimum conditions of QCM nanosensor efficiency. The results showed that QCM nanosensor has high selectivity and sensitivity for Cu(II) ions even in a wide range of 0,15 µM - 1,57 µM. The selectivity of the QCM nanosensor was shown by competitive adsorption of Co(II), Ni(II), Zn(II) and Fe(II) ions. The results are promising for developing a new strategy in the detection of environmental contaminants by combining ion imprinted polymers (IIPs) and nanosensors.