Determination of phytochemical composition and biological activities of Fumaria Officinalis

Medicinal plants have always played a pivotal role as sources for drug lead compounds. Early humans, driven by their instinct and experience treated illnesses by using plants. During the last decade there has been a growing demand for natural plants having diverse activities towards diseases especially chronic ones that need long term management. Because of this the use of medicinal plants as source materials for drug lead compounds has always been a crucial part of the drug research process. One of such plant is F. officinalis. This thesis offers valuable insights into the potential pharmacological therapeutic properties of Fumaria extracts from two different countries: Iraq and Türkiye. Assessing the inhibitory effects of acetylcholinesterase and butyrylcholinesterase enzymes, their antimicrobial activities, total oxidant levels, total antioxidant levels, oxidative stress indexes and phenolic/flavonoid content were the primary focus of this research. Results from the various tests suggest that both Fumaria extracts have promising pharmacological properties. These findings align with previous studies on Fumaria plants and confirms their pharmacological potential.