The effects of chromium picolinate on glucose and lipid metabolism in running rats

THE EFFECTS OF CHROMIUM PICOLINATE ON GLUCOSE AND LIPID METABOLISM IN RUNNING RATS Chromium picolinate and its effects on the level of lipid peroxidation increased need and responsible for glucose transport, changes in oxidative stress and serum biochemical parameters were investigated in exercise applied rats. In this study, 6 groups (Control group, Chromium picolinate, Exercise, Exercise + Chromium picolinate, Acute Exercise and Acute Exercise + Chromium picolinate) 7 including a total of 42 8-week-old male Wistar albino rats have been used. Rats were initially started to run 10 m / min. At the end of 2-weeks run period, 30 m / min, 0% grade, 30 minutes of jogging protocol has been applied with a controlled rise. After using Chromium picolinate dietary, rats were subjected to a 5 days per week for 6 weeks of exercise and the last day of exercise protocol (rats running in the treadmill until exhaustion) was applied. Data was assessed using ANOVA procedure on the package of IBM SPSS (version 22). Comparisons between groups were analyzed by the Tukey post hoc test. Data group average and standard error of mean (SEM) were calculated. For statistical significance, the probability values have been identified as significant for values that are less than P<0,05. Consequently, acute exercise increases oxidative stress, and reduced oxidative stress and chronic exercise reduces the level of lipid peroxidation. This effect shows glucose carrying regularly. In addition, Chromium picolinate consumption in rats showed the effect of increasing the level of GLUT-2 and GLUT-4. Meanwhile chronic exercise and Chromium picolinate showed a synergistic effect has been found to reduce oxidative stress. Keywords: Exercise, Chromium picolinate, Oxidative Stress, Glucose Transporters.