Effect of endoscopic bariatric treatments on nutritional status, mood and quality of life of individuals

Aldemir H. The Effect of Endoscopic Bariatric Treatments on Nutritional Status, Emotional Status and Quality of Life of Individuals. Başkent University Institute of Health Sciences, Department of Nutrition and Dietetics, Master's Thesis, 2025. This study was conducted to compare the effects of intragastric balloon (IGB) and endoscopic sleeve gastroplasty (ESG) procedures on individuals' nutritional status, eating behaviors, emotional status, and quality of life. A total of 27 volunteers (23 women, 4 men) aged 18-65 participated in the study; 14 individuals underwent IGB, and 13 underwent ESG. Data were collected preoperatively and at the 6th postoperative month using the Three-Factor Eating Questionnaire (TFEQ-Tr21), Beck Depression Inventory (BDI), Gastrointestinal Quality of Life Index (GIQLI), Pittsburgh Sleep Quality Index (PSQI), and Short Form-36 Health Survey (SF-36). The findings indicate that both procedures led to significant reductions in body weight (p<0.05). The IGB group achieved an average weight loss of 18.6±4.83%, while the ESG group achieved 19.7±7.06%. However, no statistically significant difference was found between the IGB and ESG groups regarding changes in body weight (p>0.05). Depression levels decreased significantly in both groups. The BDI scores showed a reduction of 6.9±7.03 points in the IGB group and 12±11.65 points in the ESG group (p<0.05). Sleep quality assessments showed improvements in PSQI scores for both procedures; however, no significant difference was found between the IGB and ESG groups regarding sleep quality (p>0.05). Regarding eating behaviors, both procedures resulted in significant increases in emotional eating and uncontrolled eating scores, as measured by the TFEQ-Tr21 scale (p<0.05). Endoscopic bariatric treatments not only led to changes in body weight but also influenced eating behaviors, thereby affecting individuals' dietary habits. In quality of life assessments, ESG was shown to be more effective than IGB in terms of gastrointestinal symptoms and quality of life, according to SF-36 and GIQLI scores. The data support that ESG may be a more sustainable option for patient satisfaction and quality of life among endoscopic bariatric treatments. In conclusion, ESG and IGB are effective, safe, and minimally invasive methods for obesity treatment. However, they have different impacts on nutritional status, emotional status, eating behaviors, and quality of life. The choice between these two procedures should be personalized, taking into account individuals' health status, lifestyle, and treatment goals. Keywords: Endoscopic procedures, intragastric balloon, endoscopic sleeve gastroplasty, quality of life, eating behavior