Ethyl-1-(3-nitrophenyl)-5-phenyl-3-(4-sulfamoylphenyl carbamoyl)-1h-pyrazole-4-carboxylate compound synthesis and reactions

Pyrazol and its derivatives have shown a wide range of biological and pharmacological activities of derivatives. So different ways synthesis of these compounds is increasing one-day-one. Sulfonamides were used as antibiotics in 1930s to the present day. Structure of compounds containing pyrazol, sulfonamide derivatives includes many of the pharmacological activity primarily bacteriostatic.In this study, we aimed to synthesis new heterocyclic compounds which may havebiological activity. To do this, as starting material, 4-(ethoxycarbonyl)1-(3-nitrophenyl)-5-phenyl-1H-pyrazol-3-carbonyl chloride was synthesized. Then it was transformed into a derivative compound sülfonamit. Obtained this compound nitro group (-NO2) reduced and diazonium salt was prepared and coupling reactions were done with ß-dicarbonyl compounds.Structures of these compounds which are synthesized are illuminated with , IR, 1H-NMR, 1H-DOSY and 13C-NMR spectroscophy methods.