Evaluation of BİS-GMA following orthodontic bonding with different adhesives: An in vivo study

In composite adhesives used in orthodontic clinics, ease of use, good adhesion to the enamel surface and resistance to occlusal forces are the main criteria of choice. However, besides these factors, the biocompatibility of the composite adhesives should not be underestimated. The aim of this study is to evaluate the residual Bis-GMA amount related to the use of different orthodontic bracket adhesives cured with light or chemically under in vivo conditions. 48 patients who applied for treatment in Orthodontic Department of Bezmialem Vakif University School of Dentistry were included in the study. Two light curing adhesives (Transbond XT and Opal Seal) and two chemically curing adhesives (Rely-a bond and Unite) were used to bond braces. The patients were asked to shaking with 25 ml drinking water for1 minute. A total of 144 samples were obtained at 3 instances; before bracket bonding, after bracket bonding (firs rinse) and after bracket bonding (second rinse). The samples were placed in amber colored glass bottles and stored at -20 ° C until they would be filtered through a 0.45micron filter and analyzed Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS). In all composite adhesives, BisGMA release was observed following bracket bonding. In the studied groups, the higher amount of release of residual monomer was recorded for the light curing composite adhesives especially in Transbond group(p=0.00). There was statistically no significant difference between groups in T1 and T2 periods after bracket bonding(p>0.05).