Master'sOpen Access

Design and synthesis of a potential BNCT agent capable of photodynamic therapy

2021
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Advisor: Prof. Dr. Fatih Algı ; Doç. Dr. Sedat Sürdem

Abstract (EN)

Boron neutron capture therapy is an effective treatment method developed for the treatment of various cancer diseases, especially brain tumors and melanoma cancers. In this thesis, the design and synthesis of a potential boron neutron capture therapy agent capable of photodynamic therapy were aimed. For this purpose, first of all, a new generation theranostic agent was created by combining polyhedral boron compounds and cyanine dyes with a rational design. Structural characterization of this new compound designed and synthesized, its ability to perform photodynamic therapy, ultraviolet and visible light (UV-Vis) and emission (emissivity) spectroscopy, hydrogen core magnetic resonance spectroscopy (1H NMR) and carbon core magnetic resonance spectroscopy (13C NMR) elucidated using methods

Author

Dr. Simge Pekcan

How to Cite

Simge Pekcan (Master Thesis). Design and synthesis of a potential BNCT agent capable of photodynamic therapy, 2021, Aksaray University.

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