Green synthesis of silver, cobalt and silver-cobalt bimetallic nanoparticle by using P. Harmala seed: Antimicrobial activity

Metallic nanoparticles, it has a very unique property, due to their improved size, distribution, and morphology, the synthesis of nanoparticles is increasing among researchers and their manufacture and widespread use in many scientific fields. For example, it has applications in a variety of fields, including drug delivery, optoelectronics, optical, magnetic, thermal, electrical devices, sensors, and cosmetics[32], [33]. In this study we synthesized silver nanoparticles (Ag NP), cobalt nanoparticles (CoNP), and silver-cobalt nanoparticles (Ag-CoNP), using Peganum harmala seed, extracted in three different solvents, water, methanol, and ethanol, at ambient temperature. The synthesized nanoparticles NPs were characterized using UV–Vis spectrophotometer, X-ray diffractometer (XRD), Fourier transforms infrared spectroscopy (FT–IR), energy-dispersive X-ray spectroscopy (EDS), and scanning electron microscope (SEM). Inhibitory activity was performed for the three of the synthesized nanoparticles NPs was performed by a good diffusion method against human pathogens like Escherichia coli, Staphylococcus aureus, and Candida albicans. The highest antimicrobial activity of silver nanoparticles synthesized by methanol of Peganum harmala seed extracts was found against S. aureus (16 mm) and C. albicans (16 mm) respectively. The nanoparticles NPs synthesized in this process have the efficient antimicrobial activity against pathogenic bacteria