Clinical study of interleukin-6 and some biochemical paramical in hypothyroidism patients

The aim is to study the relationship between chronic inflammation in hypothyroidism and some chemical parameters and to study changes in the levels of oxidative stress (ROS) and a decrease in the levels of antioxidants, in addition to studying the decrease in the levels of some trace elements. The patients in the study were randomly taken from hypothyroid patients coming to Baghdad Teaching Hospital, where the patient group included 120 patients with problems with hypothyroidism and compared with 120 other healthy people as a control group. Age had great importance in the development of hypothyroidism, as the results indicated the development of the disease at an advanced age. Cytokines had important indicators in patients with hypothyroidism, but relatively little clinical importance. Changes in the levels of trace elements may lead to greater chances of developing inflammatory diseases by reducing interleukin levels. The levels of the lipid profile were significantly affected in the patients, and changes in the lipid profile may be a reason for the development of hypothyroidism. Iron was not statistically significant when compared to the control group. There was great importance of Zinc in patients with hypothyroidism, which may contribute to aiding zinc absorption. Y and MDI had statistical significance, indicating the influence of antioxidants in patients with hypothyroidism.