Investigation of the effects of laser irradiation at 660nm wavelength on cell viability in the presence of gold nanoparticles in A549 lung cancer and hct116 colon cancer cell lines

The convergence of nanotechnology and laser therapy has ushered in a new era of innovative approaches to the diagnosis and treatment of cancer. With the presence of nanotechnology and laser, advanced therapies can be found as an alternative treatment for cancer. Nanotechnology has enabled the designing and fabricating of multifunctional nanoparticles with personalized properties for cancer-specific targeting, imaging, and drug delivery. These nanoparticles offer enhanced drug bioavailability, reduced toxicity, and the potential for personalized therapies. Coupled with the precision of laser technology, these nanoparticles can be activated to induce localized effects, including photothermal therapy, photodynamic therapy, and controlled drug release. The utilization of laser energy provides specific targeting, minimizing damage to healthy tissues while maximizing the therapeutic impact on cancerous cells. The challenges and prospects in this interdisciplinary field are also addressed. These encompass the need for optimized nanoparticle design, comprehensive safety assessments, and effective translation of research findings into clinical applications. Furthermore, the thesis underscores the potential of cancer nanotechnology and laser therapy in primary cancer treatment, adjuvant therapies, targeted drug delivery, and early-stage detection, which is essential. Herein thesis, lung, and colorectal cancer cell line cell viabilities are investigated with the presence of gold nanoparticles and 660 nm laser with high power.