Compare results of patients who induction wi̇th dual trigger or underwent standard trigger wi̇th ivf treatment

Objective: The aim of this study was to compare the oocyte count, metaphase II oocyte count, pregnancy and delivery results of patients who underwent standard hCG or induction with dual trigger patients undergoing ovarian stimulation due to OHSS risk in the GnRH antagonist protocol with IVF treatment. Materials and methods: For this trial, all medical files of patients who admitted to İnönü University, Turgut Özal Medical Center Reproductive Endocrinology & Infertility Department scanned. Patients who carried risk of OHSS stimuled with GnRH antagonist and received dual trigger(hCG + GnRHa) for final oocyte maturation enrolled as study group while the control group consisted of a paired standard trigger (10000 IU uhCG or 500 μgr rhCG) for age (20-40) and obtained oocyte counts 500 μgr recombinant hCG). Two groups were compared regarding oocyte count, MII oocyte count, pregnancy and birth outcomes. Results: There was no significant difference between two groups in terms of age, weight, height, BMI, duration of marriage, presence of previous pregnancy, number of previous parities, number of pre-existing children, number of previous abortus stories, number of smokers, duration of infertility, LH, E2, prolactin, TSH levels, infertility causes, and hCG dose endometrium thickness reach statistical significance. The number of oocytes obtained was significantly higher in the dual trigger group compared to the control group and MII oocyte. There was no statistically significant difference between the two groups in terms of number of pregnancies and number of deliveries. Conclusion: Although the number of oocytes and MII oocytes higher in dual trigger the standard hCG triggered patients, there was no significant difference regarding pregnancy ratio and number of deliveries. More prospective studies involving large patient groups are needed to evaluate the results of this study.