Apelin and vaspin levels in coronary slow fluid

Coronary Slow Fluid which is blamed for playing a role in the etiology of atherosclerosis is the slow movement of opac substance to distal vascular area in people with normal or subnormal coronary artery anatomy when coronaryangiography (CAG) is performed. Vasomotor disorders, oxygen- hemoglobin inappropriateness, microscular diseases and endothelial dysfunctions accused of ethyopathogenesis of Coronary Slow Fluid. On the other hand in spite of many speculations, ethyology that accused of capillery microcirculation insufficiency is a current question mark still. Although all cardiology specialists recognise Coronary Slow Fluid (CSF) well, there aren?t sufficient knowledge about clinical importance of this diseases.Apelin and vaspin which are two of the adipocytokines have been idenfied recently. Altought metabolic effects and effects on carbonhydrate metabolism of apelin and vaspin have been known, their roles on occurence of coronary athersclerosis has no been fully known yet. Currently, effect of apelin and vaspin on ethyopathogenesis of Coronary Slow Fluid can not be known. There is not any experiment about this matter. We aimed to comparison of plasma apelin and vaspin levels in CSF, coronary artery disease (CAD) and normal coronary artery (NCA) and research that value of apelin and vaspin amongst other classical risk factors that accepted in CAD.Totally subjects 90 is interned to study that 30 subjects CSF, 30 subjects is CAD and 30 subjects is control group (Normal Coronary Artery: NCA)We found apelin level relatively lower in coronary artery disease (CAD) compared to the Normal Coronary Artery (NCA) group. In addition, we also found vaspin level relatively lower in Coronary Slow Fluid (CSF) compared to the Normal Coronary Artery (NCA) group and coronary artery disease (CAD) group.In conclusıon, the levels of vaspin was found lower in Coronary Slow Fluid (CSF) in which atherosclerosis is considered to play a role in its etiology. This findings may suggest that vaspin may pay a role in the occurence of Coronary Slow Fluid (CSF). However, it is not known whether low levels of vaspin caused the occurence of Coronary Slow Fluid (CSF) or the low levels of those are resulted from the Coronary Slow Fluid (CSF).Key words: Coronary artery disease, apelin, vaspin, coronary slow fluid.