Synthesis,characterization and analytical applications of nanoparticle which have magnetic and optical properties

Synthesis, Characterization and Analytical Applications of Nanoparticle which have Magnetic and Optical PropertiesThe preparation and application of core-shell structured Fe3O4-Au nanoparticles for glucose sensing were described for the first time. Characterization of the core-shell structured Fe3O4-Au nanoparticle has proven that the resulting nanoparticles composed of Fe3O4 core and the gold shell. The pattern of Fe3O4 nanoparticles is face centered cubic with an average diameter of 9.5 nm and the initial reduction of gold on the surface of Fe3O4 particles exhibits uniform Fe3O4-Au nanoparticles with an average diameter of 12.5 nm. The saturation magnetization values for the uncoated and gold coated Fe3O4 nanoparticles were found to be 30 emu/g and 4.5 emu/g, respectively, at 300 K. Rapid and room temperature reaction synthesis of gold coated magnetic nanoparticle and subsequent surface modification provide binding properties for sensing application. Mercaptopropionic acid derivatized Fe3O4-Au nanoparticles used as a scaffold for further stepwise modification, leading to a boronic acid and the progression of binding events of glucose and was investigated. The interaction of the boronic acid modified Fe3O4-Au nanoparticles with glucose showed significant decrease of the fluorescence signal intensity.