The effects of two different immunomodulators on the calf diarries in neonatal calves

In the study, 18 new calves were used. The calves were divided into 3 groups in each group after the first controls. One of the groups was defined as control group (Group 1) and the other two groups as study groups (Group 2 and Group 3). Two different commercial immunomodulatory preparations were given to Group 2 and Group 3 while physiological saline was given for the placebo to the Control Group. Blood samples were collected at days 0, 3, 7, and 15 for immunoglobulin G (Ig) measurement and at days 0, 7, and 15 for hematological measurements. In hematological examination; Leukocyte (WBC), Lymphocyte (LENF), Monocyte (MON), Granulocyte (GRAN), Lymphocyte percentage (LENF%), Monocyte percentage (MON%), Granulocyte percentage (GRAN%), Red Blood Cells (RBC), Hemoglobin (HGB) Hematocrit (HCT), Mean Cell Volume (MCV), Mean Corpuscular Hemoglobin (MCH), Mean Cell Hemoglobin Concentration (MCHC), Red Cell Distribution Width (RDW), Thrombocyte (PLT), Mean Platelet Volume (MPV), Thrombocyte Distribution Range (PDW) was measured. WBC, GRAN, LENF%, RDW values at 0 day after birth; On the 7th day LENF and LENF% values, on the 15th day WBC, LENF, MON, GRAN, MCHC, PLT values were statistically significant differences between the groups. Immunoglobulin G levels were measured in the sera obtained from the blood samples. Periodically, feces were checked by rapid test kit. Although hematological findings showed changes according to the groups, no difference that effects study was observed. As a result of the study, IgG level was determined high on the 3rd day in Group 3. In addition, IgG levels decreased in the fastest way on control group especially on the 3rd day. We think that the newborn calves have an effect on the immunoglobulin G levels in the first fifteen days after birth.