Retrospective investigation of the relationship between non-alcoholic faty liver and homa index

SUMMARY INTRODUCTION AND PURPOSE: In our study, In patients with non-alcholic fatty liver, insulin resistance (Homa IR, Homeostatic Model Assesment Insulin Resistant) and routine liver parameters used in clinical biochemistry will be screened retrospectively. Our aim; to shed light on the etiology of increasingly extensive non-alcoholic liver fat, and to present new perspectives to the clinicians. MATERIALS AND METHODS: Our thesis study; The data of the patients diagnosed with non-alcoholic fatty liver in Sakarya University Education and Research Hospital between the period of 1.5.2015 and 1.5.2016 were retrospectively screened. In the study, radiology and biochemistry clinic HIMS data (Hospital Information Management System) was used jointly. In the radiology part of the study, retrospective Doppler Usg results of patients with NAFLD (Non-Alcoholic Fatty Liver Disease) were examined and classified according to their grade. In the part of biochemistry, Homa index and other related test were taken from HIMS. In addition, all patients' age and sex were determined included in the study. RESULT: In this study, the results of 870 patients who met our inclusion criteria were examined. Non-alcoholic fatty liver syndrome has been detected higher in male patients than female patients. In parallel with this situation, serum ALT, AST, ALP and GGT parameters were also higher in male patients. The HOMA Index was higher in children than in adults. When the HOMA index is above 2,5, it is a finding in favor of insulin resistance. However, some studies have shown that the HOMA index is higher in children than in adults. CONCLUSIONS: Sex, age and HOMA index are prominent parameters that significantly affect non-alcoholic fatty liver. The increase in 1 unit of HOMA index increased the stage of fatty liver by 1.35 fold. Being a man increases the fatty liver about 2 times. KEYWORDS: Hospital Information Management System, Non-Alcoholic Fatty Liver Disease, Homa Index, Insülin Resistance, NAFDL in the Children