Determination of D-Dimer, Cystatin-C and Pancreatic lipase values in cats with panleukopenia

The aim of this study was to determine the pancreatic lipase, d-dimer and cystatin c values in cats with panleukopenia. The material of the study consisted of 20 cats diagnosed with feline panleukopenia and 6 healthy cats of different breeds, ages and genders. Definitive diagnosis was made with clinical examination and laboratory tests in sick cats that presented with clinical findings. When the complete blood count of sick cats was examined, a significant decrease in the total leukocyte count was detected. In order to determine the biochemical values of Pancreatic Lipase, D-Dimer and Cystatin C in the control and study group cats, the samples were taken into blood tubes without anticoagulant and the values of the parameters were determined in the blood serum samples obtained with the Wondfo Fine Care Plus device. In the analyses performed, Pancreatic Lipase levels were found to be significantly higher in the study group cats compared to the control group. Again, when the control group and the study group cats were compared, it was determined that there was a numerical increase, although there was no statistically significant increase in the d-dimer levels of panleukopenia. Finally, when the cats in the control and study groups were compared, it was determined that there was no significant and meaningful change in the blood cystatin-c value. As a result, in this study, the pancreatic lipase values of cats with panleukopenia were significantly increased and it was concluded that it could be an additional biomarker in the diagnosis of the disease together with other examinations. Although the D-dimer levels did not increase statistically significantly, it was concluded that numerical changes should also be taken into consideration. Keywords: Panleukopenia, Pancreatic Lipase, D-dimer, Cystatin-c, Cat, Pancreatitis