Phytochemical composition and biological activities of some asteraceae species growing in Osmani̇ye province

In this study, the biological activities and chemical compositions of ethanol and methanol extracts of seven plant species (Anthemis cotula, Achillea falcata, Scorzonera kotschyi, Artemisia absinthium, Tanacetum parthenium, Senecio othonnae, and Tussilago farfara) collected from Osmaniye province were investigated. GC-MS analyses revealed that compounds such as caryophyllene, α-terpinenyl acetate, anethole, d-limonene, and quercetin were associated with biological activities. Phenolic analyses showed that chlorogenic, fumaric, hydroxycinnamic, and ellagic acids, as well as flavonoids such as kaempferol, quercetin, and myricetin, play an important role in the pharmacological effects of the plants. Antimicrobial tests showed that extracts of A. absinthium, A. cotula, and T. parthenium were particularly effective against Staphylococcus aureus, Enterococcus faecalis, and Candida species. A. absinthium extracts showed significant inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), while ethanol extracts of A. cotula, A. falcata, S. kotschyi, and T. farfara dose-dependently reduced cell viability in A549 lung cancer cells. In conclusion, it was determined that the plants used in our study can be considered as natural sources of antioxidants, antimicrobials, and enzyme inhibitors.