Design and manufacturing of usable membrane for polyvinyl alcohol (PVA)/ graphene oxide (GO) based biosensor application

In this study, the effect of solution parameters on the surface properties of polyvinyl alcohol (PVA)/graphene oxide (GO) nanofibers obtained by using the electrospinning method was investigated, and then the potential for use as a biosensor in biomedical applications was evaluated according to the tests performed. Polyvinyl alcohol solutions were studied on nanofiber surface production by electro-spinning method. Nanofibers made by varying the PVA concentration were observed. The created PVA solutions are removed by pouring into petri dishes, the aqueous solutions of graphene oxide in different places are separated. The dried PVA was placed in the electrospinning device and pulsed with a graphene oxide casing. The averages of the fiber diameters were taken using the analyzes made with Scanning Electron Microscopy (SEM) on the nanofiber surfaces created. According to the results obtained, the nanofiber surface properties changed with their diameters. Viscosity and electrical conductivity experiments were carried out on nanofiber membranes produced for the use of biosensors. Protective effects against harmful organisms, cell testing and mechanical testing to maintain durability of the fabricated nanofibrous membrane intended to be a wound dressing. Thermogravimetric analyzes (TGA) were performed to examine the heat counterweight changes and heat tables. As a result of running and testing, measurement values have a significant influence on nanofiber surface properties and diameter values. Examined test results are predicted to be appropriate based on assessments of dressing use. Keywords: Electrospinning, nanofiber, biosensor, polyvinyl alcohol, graphene oxide