Evaluation of the relationship between the quality of life, emotion and nutrition in adults with primary hypothyroid

This study was conducted with a total of 106 individuals, 84 females and 22 males, who voluntarily accepted to participate in the study, who were diagnosed with overt hypothyroidism and subclinical hypothyroidism by the doctor who applied to the Endocrinology and Metabolism outpatient clinic of Çukurova University Faculty of Medicine Balcalı Hospital between November 2019 and February 2020. A questionnaire was applied to the individuals participating in the study using face to face interview method, food consumption records and anthropometric measurements were taken and some biochemical parameters were analyzed. Thyroid Patients Quality of Life Scale (ThyPRO) was used for the quality of life of the patients, and the Profile of Mood States (POMS) scale was used to evaluate their mood. Participants were divided into two groups as overt and subclinical hypothyroidism. 44 patients with overt hypothyroidism and 62 subclinical hypothyroidism were included in the study. The mean age of patients with overt hypothyroidism was 45.30 ± 9.98 years, and the mean age of patients with subclinical hypothyroidism was 44.48 ± 10.80 years. No significant difference was found between the two groups by age groups (p> 0.05). When evaluated according to body mass index (BMI) classification; 57.1% of males in the overt hypothyroid group and 27% of females were slightly obese (BMI 25-29.9 kg / m2), none of males and 21.6% of females were obese (BMI 30.0 kg /m2), male individuals It was determined that 42.9% of the female individuals and 45.9% of them were in the normal BMI group (BMI 18.5-24.9 kg /m2), none of the males and 5.4% of the females were in the weak BMI group. In the subclinical hypothyroid group, 53.3% of males and 40.4% of females were slightly obese (BMI 25-29.9 kg /m2), 13.3% of males and 12.8% of females were obese (BMI 30.0 kg / m2), 33.3% of males and 42.6% of females were normal (BMI 18.5-24.9 kg / m2) and none of males and 4.3% of females were in the weak BMI group. The average daily energy intake values of individuals in the overt hypothyroid group were 1634.7 ± 014.06 kcal, and the average daily energy intake values of individuals in the subclinical hypothyroid group were 1516.3 ± 332.45 kcal. Average percentage of the daily energy of individuals coming from protein; It was found to be 19.4 ± 5.90% in the overt hypothyroid group and 19.9 ± 6.05% in the subclinical hypothyroid group. Looking at the ratio of daily energy from fat; 45.1 ± 6.62% in the overt hypothyroid group and 42.9 ± 6.12% in the subclinical hypothyroid group. Energy from protein and fat is well above the recommended level. When the daily diet and vitamin B12 intake of the individuals participating in the study were compared by gender, it was found to be significantly higher in men than in women. The dietary intakes of phosphorus, zinc, iron and sodium minerals were found to be statistically significant when compared between the two groups. In addition, according to the comparison of the groups with gender, the amount of phosphorus intake by diet was found to be statistically significant. When biochemical parameters were compared between the two groups, vitamin D, hemoglobin and sodium levels were found to be significantly lower in the overt hypothyroid group than in the subclinical hypothyroid group. When comparing the 13 variables of the ThyPRO Quality of Life Scale between overt and subclinical hypothyroid patients, the mean hyperthyroid and hypothyroid symptom subscale score was found to be significantly higher in the overt hypothyroid group. When comparing individuals according to gender, the mean hyperthyroid symptom and anxiety subscale score was found to be significantly higher in women compared to men. The hyperthyroid and hypothyroid symptom subscale mean score is significantly higher in individuals who received hormone replacement therapy compared to those who did not. Eye symptom subscale mean score was significantly higher in individuals who do physical activity than those who do not. When 6 variables of the Profile of Mood States Mood Profile scale were compared between overt and subclinical hypothyroidism patient groups, no significant difference was found between the subscale mean scores. Likewise, when a comparison was made according to gender, age groups, educational status, duration of hypothyroidism diagnosis, taking hormone replacement therapy and performing physical activity, no significant difference was found. As a result, it was determined that individuals diagnosed with hypothyroidism had low quality of life due to various factors, and it was determined that physical and mental health improvement studies should be carried out in order to increase the quality of life in these individuals.