The relationship between radial artery spasm and pon1, ares and TTL in patients with radial angiography

INTRODUCTION AND AIM: Some patients may develop spasm in interventional angiography. The causes of spasm in the radial artery have also been the subject of scientists. The aim of this study is to investigate the relationship of the spasm during angio between PON1, ARES and TTL. MATERIALS AND METHODS: Plasma of blood of the study group (34 controls, 34 patients with angiography) for approximately 7 months was collected to use Total Thiol (TTL), Paraoxanase (PON1), Arylesterease (ARES). The patient plasma was stored at -80°C in eppendorf tubes with lids. Rel Assay Diagnostics SPSS 23 package environment. RESULTS: TTL levels in the patient group (mean ± standard deviation = (360,29 ± 75,50μmol / L) were significantly lower than the control group (482,25 ± 39,65 μmol / L); (t(66)=8,339, p<0,001). ARES values of the patient group ( 11,30 ± 2,88U / L) were significantly lower than the control group (14,28 ± 2,49U / L); (t(66)=4,569, p<0,001). In addition, Mann-Whitney U test was used to compare Pon1 values. Although there was no statistical significance (U=495, p=0,309), PON1 values in the patient group (median = 140,78U / L) were found lower than the control group (153,65 U / L) CONCLUSION: Plasma values in patients undergoing angiography revealed a decrease in lipophilic antioxidant properties. A significant decrease in patient ARES values is indicative of this. On the other hand; PON1 in the control group is not as high as expected, 82.35% of the control group can be explained by smoking. However, significantly lower values of TTL in the patient group indicate that the thiol / disulphide balance should also be examined in these patient groups. Keywords: Arylesterase, Paraoxanase-1, Radial angiography, Radial Artery Spasm, Total thiol.