The investigate of genotoxic effects of brilliant blue and sunset yellow from food colorant additives in human peripheral lymphocyte cultures

Mutagenic, carcinogenic, teratogenic and toxic factors, strong, people and other genotoxic or mutagenic effects on organisms in the study of various cytogenetic methods are used. In this study, it was investigated that the effects of Brilliant Blue and Sunset Yellow from food colorant additives on micronucleus, mitotic index and replication index will in peripheral blood lymphocytes. According to the results of the genotoxic tests, the brilliant Blue and sunset Yellow are increased the frequencies of the micronucleus and decreased the rate of mitotic and replication indexes. The results showed that these food colorant additives are potential genotoxic and cytotoxic compounds at high concentrations.