Correlation between rotational thromboelastometry fibtem parameters with laboratory fibrinogen levels

ABSTRACT Introduction: Rotational Thromboelastometry (ROTEM) is an analysis that gives general information about hemostatic system by evaluating visco-elastic and mechanical properties of clot. ROTEM has been used frequently to evaluation of coagulation system, and in the determination of the need of blood and blood products for transfusion. The aim of our study was to examine whether ROTEM FIBTEM parameters correlate with laboratory fibrinogen concentration with Clauss method. Materials and Methods: Thirty donors who were planned to undergo donor hepatectomy for live donor liver transplantation were included in the study. Intraoperative simultaneous blood samples were taken from the patients and was measured by the Clauss method of the fibrinogen concentration and MCFFIBTEM as the nearest parameter to the fibrinogen of ROTEM. Results: Although the presence of hypofibrinogenemia was seen in 76% of the fibrinogen levels measured by the Clauss method, MCFFIBTEM was measured at a normal range in the patients of 96.6%. In our study, high degree of correlation was not found between Clauss fibrinogen concentration and MCFFIBTEM. Conclusion: There was a weak correlation between laboratory Clauss fibrinogen concentration and FIBTEM in our study and larger patient studies were needed. Key Words: ROTEM, FIBTEM, MCF, fibrinogen, donor hepatectomy