Comparison of antiseptic efficacy of octenidine hydrochloride, chlorhexidine digluconate and povidone iodine for the applications of central and peripheral venous catheterisation

The purpose of this study is to compare the antiseptic efficacy of octenidine hydrochloride, chlorhexidine digluconate and povidone iodine for the applications of. Central and peripheral venous catheters is often used in patients, especially in intensive care units for such purposes; fluid and electrolyte therapies, blood and blood products, the use of some antibiotics, chemotherapeutics, and hemodynamic monitoring of patients. The catheter site must be cleaned quickly and efficiently with an antiseptic agent, to prevent infections nevertheless, , most of the time, catheters inserted under emergency conditions, so that fast and effective cleaning of the skin is important. After approval of the ethics committee and informed 90 patients aged between 18-65 years were included in the study. The patients were randomly divided into three equal groups. Skin disinfection was performed. In the first group with 0.1% octenidine and in the second group with 10% povidone iodine, in the third group with 1.5% chlorhexidine gluconate. Samples were taken with the swabs from the skin before and after the skin antisepsis . The samples were applicated first in the liquid medium and then blood and EMB agar culture media. They were incubated for 24-48 hours at 37 ° C and colonies were counted after 24 hours. All groups were similar in terms of the demographic data. The positive results is seen as follows, 4 cases (13.3%) were foundto be positive in the OHC group, 5 cases (16.7%) in the PI group, 2 cases (6.7%) in the CHG group As a result, statistically significant difference was not found in terms of antimicrobial effectiveness of octenidine hydrochloride, chlorhexidine digluconate and povidone iodine for the applications of central and peripheral venous catheters. Key words: Central and peripheral venous catheterization, antisepsis, octenidine hydrochloride, povidone iodine, chlorhexidine gluconate, intravenous cannulation