Statinlerin yan etkileri ve rabdomiyolizin maliyet hesaplamasi

Purpose: The main aim of the study is to highlight the adverse effects of statins and to calculate the cost of rhabdomyolysis treatment for one patient in Turkey which is a rare but the most serious adverse effect of statins that cause to stay in hospital. In addition, cost of prevention of this adverse effect has also been calculated. These two results have been compared.Materials & Methods: A review of national and international literature has been searched by using Ulakbim, Pubmed and Sciencedirect web sites. IMS data for statins have been used and safety of statins have been searched by using internet web sites among different countries? health authorities. In order to calculate the direct cost of muscle related adverse effect, Turkish Ministry of Health Health Application Announcement prices have been taken into consideration for laboratory tests. For the calculation of the cost of drugs used in the treatment of adverse effect, prices have been gathered from RxMediaPharma web based programme. Prices that have been used for calculation are the minimum prices which constitute the lowest prices of the price band reimbursed by Social Security Institution (SSI). In order to validate all of these data, prices of laboratory tests and drugs have been obtained from Kırklareli Public Hospital Accounting House and Şişli Etfal Public Education and Research Hospital Accounting House.Findings and conclusion:Cost of prevention of statin-induced muscle adverse effects is lower than the cost of the adverse effect in case of nonprevention or ignorance. In addition because of the treatment of acute tubular necrosis requires dialysis lifelong, cost of the adverse effect will be higher than the expected. At that point, it is very important to increase the patients? awareness and the doctors? attention for muscle related adverse effects of statins. Thus, all the costs related to statin-induced muscle adverse effects can be minimised.