Study of the changes that occur in some biochemical variables after cholecystectomy for patients in Al-Anbar governorate /Iraq

The study included (90) Iraqi persons with age ranged from (20 - 70), that divided for two groups, group (1) control group consist of 30 healthy persons (males and females) and group (2) consist of 60 patient had a cholecystectomy, samples were obtained from Al-Ramadi teaching hospital and Haditha general hospital during the duration of October 2020 to March 2021, and measuring concentrations of TSB, ALT, AST, ALP, cholesterol, TG, LDL, HDL, VLDL, LDL, S. amylase, S. lipase, and CCK. Regarding the age of all participant the Mean ± SE of patient group was (45.47 ± 1.57) that is lower than the control group (50.53 ±1.73) with p- value 0.05 indicate a difference of statistical significant between the two group. The TSB mean level of patient group was 0.81 ± 0.02 that is statically different from mean level in control group (0.74 ± 0.01), with p-value 0.04. TG and VLDL result showed a statistical difference between patient and control group, p-value was 0.01 for both markers. Measuring CCK for both group indicate a statistical significant difference in between as p- value 0.008. Keywords: Cholecystectomy, Liver function test, Lipid profile, Amylase, Lipase and cholecystokinin