Suda asılı kalan kuantum noktacıkların ve hibrid nano parçacıkların geliştirilmesi

Nanoparticles are one of the major areas of nanotechnology where size confinement provided a dramatic differentiation in material properties enabling numerous applications for many disciplines. Among these superparamagnetic iron oxides and semiconductor quantum dots are possibly the most widely studied nanoparticles due to their great potential in broad application areas, most significantly in health, defense and energy. The target area for the nanoparticles described in this thesis is the biotechnology and medicine.The premise of this thesis is to synthesize aqueous magnetic luminescent hybrid nanoparticles. To achieve such a goal, highly luminescent, water soluble and biocompatible colloidal CdS and CdTe QDs were synthesized first. Then, as prepared colloidal QD solution was used to coat and stabilize magnetic iron oxide nanoparticles in a unique, safe and economical one-pot reaction. The approach involves utilization of biocompatible multifunctional coating molecule, primarily L-cysteine, which can stabilize both nanoparticles and keep them in water simultaneously. The cell uptake and cell viability studies confirmed suitability for bio applications.Development of such a multi-functional single entity will provide dual sensing modes (optical and magnetic detection) as well as combined sensing and separation capabilities.