Synthesis and anticancer activities of some metal complexes involving N-heterocyclic carbene ligands
2023
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Advisor: Prof. Dr. Ali Karaipekli ; Dr. Öğr. Üyesi Ahmed Hassoon Mageed
Abstract (EN)
In this study, a series of novel copper(I)-NHC and silver(I)-NHC complexes were synthesized. Copper and silver-NHC complexes were synthesized by reacting metal sources with imidazolium salts in the presence of a mild base. The ligands and complexes were characterized by FTIR, 1H NMR, and 13C NMR spectroscopy. The Cu(I) and Ag(I)-NHC complexes were tested against breast cancer cells MCF7. The results showed that Cu(I) and Ag(I)-NHC complexes have promising effects as antiproliferative activity against breast cancer cells compared with normal cells.
Author
Dr. Israa Samı Hadı Alkhudharı
How to Cite
Israa Samı Hadı Alkhudharı (Master Thesis). Synthesis and anticancer activities of some metal complexes involving N-heterocyclic carbene ligands, 2023, Çankırı Karatekin Üniversitesi.
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