Determination of parthenolide in tanacetum argenteum (LAM) willd. subsp. argenteum

In this study, the leaves, flowers and stems of endemicTanacetum argenteum subsp. argenteum collected from Kayseri-Binboğa mountains were analyzed for their parthenolide content by using HPLC/LCMS method. There were no reports in the literature on the parthenolide content of Tanacetum argenteum subsp. argenteum.Parthenolide amount in the stems (%0,129) and flowers(%1,585) of Tanacetum argenteum subsp. argenteum are in accordance with the reported amount for Tanacetum parthenium in the literature (%0.1-1.68). Parthenolide amount of the leaves of Tanacetum argenteum subsp.argenteum (%2.261) is much higher than the required amount for the aerial parts of Tanacetum parthenium (%0,2) in European Pharmacopoeia andESCOP Monographs.