The effect of one-lung ventilation kongnitif functions

Introduction and Objective: Postoperative cognitive dysfunction (POCD) is frequently seen in patients of all age groups, especially advanced age, after major surgery and may persist for months. Although its etiology is multifactorial, factors affecting the balance of cerebral oxygen delivery and consumption are blamed. For this reason, it was aimed to evaluate whether patients developed POCD by evaluating POCD with mini-mental state test in thoracic surgery patients who underwent single lung ventilation (SLV), which can progress with serious complications such as hypoxia. Materials and Methods: After the approval of the Ethics Committee, patients between twenty years and seventy-two years of age who gave informed consent, candidates for single lung ventilation in thoracic surgery and those who agreed to participate in the study were included in the study. The anesthesia protocol was applied the same way in all patients. Cognitive assessment was conducted one day before the operation, one day after the operation and three days after. For this purpose, mini-Mental Status Assessment test was used. SPSS 22.0 was used for statistical analysis. Results: 30 patients were included in the study. Postop cognitive dysfunction (POCD) was detected in 26% of patients who underwent single lung ventilation (SLV). The mini-mental state test of the patients showed a difference in terms of cognitive dysfunction between preoperative and postoperative day 1 and day 3. However, no difference was detected between Day 1 and Day 3 after surgery. Conclusion: Early cognitive dysfunction is observed in patients undergoing single lung ventilation in thoracic surgery. Surgical time, anesthetic drugs, and patient-related parameters are effective, and patients should be closely monitored in terms of cognitive functions of the patients, in close follow-up and after surgery. Keywords: Single lung ventilation, Cognitive dysfunction, Mini-mental state test