The Effect of diagnostic ultrasound on the rat kidney tissues

The use of diagnostic ultrasound has an exemplary record of safety, particularlywhen compared with other medical imaging techniques. There has beengrowing interested in estimating the degree of temperature caused by thediagnostic ultrasound in clinical and theoretical practice, in recent years. Boththeoretical and experimental methods have been suggested for estimating theheating potential or mechanical hazard of diagnostic ultrasound. To investigatethe biological effects of ultrasound exposure to the kidney tissue, the antioxidantenzyme activities and malondialdehyde (MDA) levels, as a lipid peroxidationend product, were evaluated. Superoxide dismutase (SOD) activity was slightlydecrease in B-mode compared control, but in doppler group significantlyincreased p<0.05. CAT activities were significantly increased both B-mode anddoppler groups versus control group p<0.05, p<0.005 respectively. GSH-Pxactivities were significantly elevated in doppler groups (p<0.05), compared tocontrol. MDA levels were significantly inreased in doppler group versus controlgroup p<0.05. As a result, doppler ultrasound due to heating and/or mechanicaleffect can produce free radical, which causes hamful effect partiularly ofpregnancy in first trimester.