Synthesis and characterization of new acridine derivatives

Acridines are hetero-ring organic compounds having a multi-ring system and plane geometric structure. They are generally used in the synthesis of dyes and some important drugs. Up to now, numerous acridine derivatives were synthesized to investigate their biological activities and so efforts in this area continues to increase. In this study; synthesis of novel acridine derivatives which may have various biological activities. In the first part of the study; 1,3-diphenyl-1H-pyrazole-4-carbaldehyde, 3-(3-nitrophenyl)-1-phenyl-1H-pyrazol-4-carbaldehyde, 3-(3-bromophenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde and 3-(3-chlorophenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde. In the second part of the study, these compounds synthesized according to the literature; 5,5-dimethylcyclohexane-1,3-dione, cyclohexane-1,3-dione and 3-aminobenzene-1-sulfonamide were synthesized to synthesized new acridine derivatives which are target molecules. The synthesised compounds Were characterized by following FT-IR, 1H-NMR, 13C NMR and mass spectroscopic methods. Keywords: Acridine, Acridindione, β-diketone, Carbaldehyde, Heterocyclic Compounds.