Retrospective examination of patients diagnosed with COVID-19 treated in icu

Coronavirus Disease-19 (COVID-19) is a multisystemic disease that causes acute respiratory distress syndrome (ARDS), sepsis, septic shock, myocarditis, arrhythmia, cardiogenic shock or multiple organ failure. In this study, it was aimed to retrospectively evaluate the patients followed in the intensive care unit. The data of 200 patients treated in the intensive care unit with the diagnosis of COVID 19 were analyzed retrospectively. Basic characteristics, comorbidities, clinical conditions during the intensive care unit admission, respiratory support treatments and laboratory findings were analyzed. Of the patients, 124 were male and 76 were female. Mortality occurred in 143 of 200 patients. The mean age of patients who died (70.5 ± 14.02) was higher than those who survived (64.3 ± 16.25). 154 of the patients had findings consistent with COVID 19 in the chest tomography. The SOFA score of the patients was 5 (0-17) and the APACHE II score was 16 (5-37) at the time of admission to the intensive care unit. The median length of stay of the patients in the intensive care unit was 10 (1-64) days. The APACHE II score and SOFA score of the patients who died in the intensive care unit admission were significantly higher than the patients who survived. Mortality occurred in 141 of 180 patients who developed ARDS. The mortality rate in patients who did not develop ARDS was 10%. The mortality rate was significantly higher in patients who developed ARDS. While the median lactate values were 2.30 (1.80-3.60) in the patients who died at admission to the intensive care unit, it was 2 (1.50-2.50) in the patients who survived and 85 (82-90) in the patients who survived, and 89 (82-90) in the patients who died. (94-92). The percent change of lymphocyte value on the 14th day compared to the value at admission to the intensive care unit in the patients who died was a 27% decrease, while it was a 15% increase in the survivors group. The percent change in the PaO2/FiO2 ratio on the 14th day was 29% increase in the deceased group and 115% increase in the survivors group. While the LDH value at admission to the intensive care unit was 630 (37-6517) in the deceased group, it was 511 (216-1434) in the survivors group. The 7th day percent change in LDH value was 6% increase in the deceased group and 16% decrease in the survivor group. The mortality rates of clinical conditions such as sepsis, ARDS, MAS, coagulation disorder and kidney failure in COVID-19 patients are quite high. LDH, SpO2, PaO2/FiO2 ratio and lactate values were found to be useful tests in the prediction of mortality. In the follow-up of these patients, lymphocyte count, CRP, AST, D-dimer and ferritin values will be useful. Keywords: COVID-19, Intensive Care Unit, Mortality