Synthesis of some derivatives of oxazolidyne and 2-amino-4-chloromethyl thyazol,spiro[4,4]nonan-bis-thyazol

In this work, first 1,3-dicholoro acetone (1) was synthesized. Then, 3,8-dithyo-1,6-diazospiro[4,4]nona-1,6-dien-2,7-diamine (2) and 4-chloromethyl-2-methyl-1,3-thiazol (3) compound were synthesized by reacting with thioure and the compound (1) mentioned. The schiff bases were prepared by reaction of (3) and aldehyde such as benzaldehyde, p-hydroxybenzaldehyde, 2-hydroxybenzaldehyde. Bis-thiazol derivatives were synthesized by reaction of (2) and chloroacetylchloride, benzaldehyde, p-hydroxybenzaldehyde and salisyldealdehyde. Also, its diester derivative was prepared by reacting with (2) and ethylmethane tricarboxilate. Dithiocarbomat derivatives were obtained by reaction of chloromethyl thiazole and carbomat salts. Processes of purification was carried out cristallization and precipitant. Structure of compounds synthesized was characterized by elementel analysis, IR, 13C and 1H-NMR techniques.