Evaluation of coenzyme Q10 and total antioxidant capacity in sera of patients age 30-80 with renal failure

This study was designed as a biochemical study of antioxidant and Q10 coenzyme using biomarkers and their role in laboratory diagnosis in a patient with renal failure. A group of 82 a sample with renal failure who were treated in Kirkuk State Hospital and 30 healthy samples aged between 30-80 years were included in the study. Samples were collected in the period 1/2 / 2021 - 30/4 / 2021. The samples were divided into two groups: Group I: patient: Group II: control. The study included measurement of some biochemical variables such as (Urea, Creatinine, Albumin, Cholesterol, Co enzyme Q10, Antioxidants). The results showed the following points, the mean level of urea and creatinine was increased (P = 0.0001), they were significant in the first group. The mean concentrations were (149.40a ± 39.53 mg/ dL and 6.57a ±2.32 mg/day). It doesn't matter in albumin and cholesterol. The mean concentrations were (3.99 a ± 0.40 mg/dL and 198.61 ± 36.81 mg/dL) compared to the control group, which showed (3.99a ± 0.40 mg/dL and 198.61 A ± 36.81 mg/dL. The study also showed a significant decreases in Coenzyme Q10 concentration level (P = 0.040) in patients with renal impairment aged 70-80 years, there was no significant change in the p-value of antioxidants at 0.813 (0.96b ± 0.43μL) when compared with control age.