Synthesis and characterization of new aryl sulfonyl hydrazones derivated from 4-fluorobenzenesulfonyl hydrazide

Sulfonyl hydrazone scaffold has important role in medicinal chemistry and exhibited different biological activities such as antioxidant, anticancer, anticonvulsant, antidepressant, antimicrobial, anticholinesterase, analgesic and anti-inflammatory activities. In the scope of this research, 4-fluorobenzenesulfonyl hydrazones were obtained by the reaction of 4-fluorobenzenesulfonyl hydrazide with some substituted aldehydes in methanol. Physical and chemical properties of compounds have been characterized and comfirmed by IR, 1H NMR, 13C NMR, mass spectroscopy and elemental analysis.