Assessment of leptin levels and lipid profile among type 2 diabetic patients in comparison to non type 2 diabetics

The current research aims to assessment in vitro the leptin levels and lipid profile among type 2 diabetic patients in comparison to non diabetics and the changes in leptin, lipid profile, Glucose and some biochemical tests with type 2 diabetic patients in comparison to non diabetics men. 110 Patients with T2DM and healthy persons (Controls group) were evaluated with looking into account age and weight, Group A (Control Group 55 without T2DM), Group B (55 With T2DM). The levels were studied Leptin, FBS, HbA1c, total cholesterol levels, HDL, LDL, VLDL, and TG in all blood serum samples of patients and controls for all cases. The results indicate the importance of leptin and the effect of its levels in patients with diabetes mellitus, which indicates the clinical importance of diagnosing leptin levels with age and triglycerides when directly treating these patients. The relationship between leptin levels and HOMA-IR was more pronounced and significant among obese T2DM subjects. All in all, it can be recommended that more studies should be conducted in more groups in order to fully reveal the relationship between leptin and other chemical tests in patients with diabetes mellitus. Inaddition, some tests must be added, especially the hormone insulin, in order to conduct a more important study.