Investigation of phytochemical analysis and biological activities of some endemic Astragalus species
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Abstract (EN)
In this study, their secondary metabolites (phenolic compounds and fatty acides), and biological activities (antiproliferative - cytotoxic activity) of endemic three Astragalus species (A. dipsaceus Bunge, A. karamasicus Boiss. & Bal., A. sigmoideus Bunge) in were researched. For this purpose, firstly, plant samples will be collected in the natural environment. They will be dried under appropriate conditions and they will be ready for experimental work. Then secondary metabolites from the plant will be extracted and determined antiproliferative - cytotoxic activities. Hexane extracts will be characterized by GC-MS and other extracts will be determined by HPLC-TOF/MS. Extracts that were obtained from plants will be used for the anticancer activities against rat brain tumor (C6) and human cervical cancer (HeLa) cells. The extracts that have high antiproliferative activities will be examined cytotoxic activities.
Author
Murat Temirtürk
How to Cite
Murat Temirtürk (Master Thesis). Investigation of phytochemical analysis and biological activities of some endemic Astragalus species, 2017, Çankırı Karatekin Üniversitesi.
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