Development of antiperspirant formulation based on double emulsion

In this study, lavender oil is used to give pleasent odor and aluminum chlorohydrate is used due to its effect on decreasing the perspiration. Two actives were formulated with suitable emulsifiers to obtain a stable multiple emulsion. Suitable emulsifiers were chosen due to their HLB value according to manuscript and literature. Aluminum salts are the main topical agents for hyperhidrosis which have antiperspirant activity that decreases perspiration. When these salts are used in cosmetics formulations, duration of effect is often limited to 48 hours. By microencapsulating antiperspirant salts the insulation from the surroundings, and controlled released could be achieved, so securing a long shelf life. In order to overcome these problems both were used in small amounts, in a formulation of a double emulsion. So that, both were chosen to be used in small amount by the technique of double emulsion. The cosmetic products generally contain 10% of aluminum chlorohydrate on the market. The objective of this study was to investigate and to obtain the optimum antiperspirant ratio for formulation of stable double emulsion. In this project the ratio of aluminum chlorohydrate was determined as 1% in double emulsion formulation. For this purposes, optimum conditions were determined according to experimental results of particle size, stability and migration studies. Finally, the most stable double emulsion (F4) resulted poly dispersity index of 0.238 at the end of the 13th day and with an average globule size of 3.9 µm and 1%, which is 10 times lower dosage, containing aluminum chlorohydrate was formulated to be used as antiperspirant cream/roll on. The second aim is that the aluminum chlorohydrate formulated in the inner phase of the double emulsion stays there or is slowly released for the final product to show desired antiperspirant properties. For this purposes, migration over time was detected. As a result, it was clearly observed that incorparation of viscosity enhancer was delayed the migration. Due to the increased amount of viscosity enhancer, the migration rate was slowed down, improving the stability. Keywords: Aluminum salts, lavender oil, multiple emulsion, double emulsion, microencapsulation