Evaluation of midterm outcomes of total knee arthroplasty in hemophilic arthropathic patients: Retrospective study

Evaluation of Midterm Outcomes Of Total Knee Arthroplasty In Hemophilic Arthropathic Patients: Retrospective study Haemophilia is an X-linked, recessive inherited, congenital bleeding disorder caused by a deficiency of coagulation factor 8 or 9. Hemophilia has an estimated frequency of approximately one in 5,000- 10,000 births. Hemophilia A is caused by factor 8 deficiency and hemophilia B is caused by factor 9 deficiency. Hemophilia A is more common than hemophilia B, representing %80 of the total hemophilia population. Intra-articular and intra-muscular bleeding occurs commonly. Recurrent bleeding attacks in the joint cause inflammation of the synovial membrane (chronic sinovitis). As a result progressive degeneration in the joint causes hemophilic arthropathy. The aim of this study is to evaluate the clinical, radiographic and functional midterm results of total knee arthroplasty performed to patients with end stage knee hemophilic arthropathy, compare preoperatively and determine the effectiveness of this method. In the period 2012-2020, 14 total knee arthroplasties were perfomed in 11 men with severe haemophilic arthropathy included in this study. Patients were evaluated retrospectively. American Knee Society scoring, Total knee arthroplasty radiological evaluation scoring and Visuel Analogue Scale were used to evaluation. Arnold-Hilgartner and Petterson scales were used for staging of hemophilic arthropathy. We evaluated the results obtained in our study separately in preoperative and postoperative periods and compared them with the literature datas. We found that total knee arthroplasty performed to patients with hemophilic arthropathy increases joint range of motion, improves pain scores and is an effective treatment for obtaining a functional knee.We observed that complications could be minimized with close follow-up and multidisciplinary team working.