The use of surface - printed electrodes modified with carbon derivatives in racemic drugs separation

In this thesis, carbon-based electrodes and electrochemical sensor studies were carried out to distinguish the enantiomers of chiral compounds that have a significant role in multidisciplinary science. For this purpose, derivatives of carbon material such as graphene oxide / cyclodextrin (GO / β-CD) and carbon nanotube / β-cyclodextrin (CNT / β CD) were synthesized by chemical reduction method which has attracted great interest in electrochemical sensor applications due to its superior properties in recent years. The characterizations of the carbon-based electrocatalyst were characterized by X-ray diffraction (XRD) with the electrode surfaces by scanning electron microscopy (SEM).The carbon-based materials obtained which graphene oxide / surface printed carbon electrode (GO / SPCE), carbon nanotube / surface printed carbon electrode (CNT / SPCE), graphene oxide /-cyclodextrin (GO / β -CD / SPCE) and surface printed carbon electrode / β-cyclodextrin (CNT / β-CD / SPCE) were produced by modifying the surface of the surface-printed carbon electrodes (SPCE).The efficiencies of the electrocatalysts were characterized by cyclic voltammetry (CV) techniques. Enantioselective chiral differentiation studies were carried out against chiral compounds of electrodes used as enantioselective chiral sensors in electrochemical studies and respectivelyFluosectin which is an antidepressant drug active ingredient in racemic form and Ketoprofen which is an active and pain killer antipyretic drug, enantiomers were distinguished electrochemically from each other.