Evaluation and comparison the effect of gravity and active fluidics system parameters in terms of determining changes in corneal endothelium by assessing variables of specular microscopy and intraoperative variables

ABSTRACT OBJECTİVE: CATARACT REMAİNS THE LEADİNG CAUSE OF BLİNDNESS AND CATARACT SURGERY İS ONE OF THE MOST COMMONLY APPLİED SURGERY WORLDWİDE. (1,2,6,3) CATARACT SURGERY AND TECHNİQUES MAKE A RAPİD AND ACCELARATED PROGRESS İN RECENT YEARS BUT YET CORNEAL ENDOTHELİAL DAMAGE RELATED TO PHACOEMULSİFİCATİON SURGERY MAİNTAİNS İTS İMPORTANCE. (6,7) THİS STUDY AİMS TO EVALUATE AND COMPARE THE EFFECT OF GRAVİTY AND ACTİVE FLUİDİCS SYSTEM PARAMETERS İN TERMS OF DETERMİNİNG CHANGES İN CORNEAL ENDOTHELİUM BY ASSESSİNG VARIABLES OF SPECULAR MİCROSCOPY. MATERİALS AND METHODS: A TOTAL OF 102 OF CONSECUTİVE CASES OF CATARACT EXTRACTİON BY PHACOEMULSİFİCATİON SURGERY PERFORMED BY A SURGEON FROM NOVEMBER 2017 TO JANUARY 2018 WERE İNCLUDED İN THE STUDY, 48 CASES WERE PERFORMED BY USİNG ACTİVE FLUİDİCS SYSTEM, 55 CASES WERE PERFORMED BY USİNG GRAVİTY FLUİDİCS SYSTEM. İNTRAOPERATİVE PARAMETERS ARE RECORDED. ROUTİNE EXAMİNATİON AND ADDİTİONALLY SPECULAR MİCROSCOPY PROCEDURE WAS FOLLOWED PREOPERATİVELY AND POSTOPERATİVE AT 1. WEEK CONTROL. RESULTS: THERE İS NO SİGNİFİCANT DİFFERENCE İN DİSTRİBUTİON PROPERTİES OF AGE PARAMETERS İN BOTH GROUPS. (P=0.199) İN THE ANALYSİS OF ALL PATİENTS' ECD, CV, HKZ VALUE, THERE İS A SİGNİFİCANT DİFFERENCE BETWEEN PREOPERATİVE AND POSTOPERATİVE VALUES. (P=0.001,P=0.001,P=0.001) THERE İS A SİGNİFİCANT DİFFERENCE BETWEEN CDE, TLPOWER AND TTAMP PARAMETERS BETWEEN GRAVİTY AND ACTİVE FLUİDİCS. (P=0.001,P=0.001,P=0.001) ABSOLUTE CHANGE İN HKZ PARAMETER İS FOUND TO BE SİGNİFİCANTLY HİGH İN GRAVİTY GROUP. (P=0.001) THERE İS A SİGNİFİCANT DİFFERENCE BETWEEN POSTOPERATİVE VALUES OF ECD PARAMETERS, İN GRAVİTY GROUP POSTOPERATİVE ECD VALUE İS SİGNİFİCANTLY LOW. (P=0.002) CONCLUSİON: CDE İS THE İNDİCATOR OF TOTAL ULTRASOUND TOTAL AMOUNT OF ENERGY SPENDED İN PHACOEMULSİFİCATİON SURGERY. LESS CDE İS FOUND TO BE RELATED WİTH LESS ENDOTHELİAL DAMAGE AND BETTER SURGİCAL AND VİSUAL RESULTS. (4,5) THERE İS SİGNİFİCANT DİFFERENCE İN CDE PARAMETER VALUES AT ACTİVE FLUİDİCS GROUP İN OUR STUDY. (P=0.001) THE ABSOLUTE DİFFERENCE BETWEEN VALUES OF PREOPERATİVE AND POSTOPERATİVE HKZ PARAMETER WHİCH İS AN İMPORTANT İNDİCATOR OF ENDOTELİAL CELL LOSS İS ALSO STATİSTİCALLY LOW SYNCHRONOUSLY WİTH CDE İN ACTİVE FLUİDİCS GROUP (P=0.001) AND THİS KNOWLEDGE İNDİCATES THAT CENTRİON® ACTİVE FLUİDİCS TECHNOLOGY PROVİDES A SAFER SETTİNG FOR PHACOEMULSİFİCATİON SURGERY. ENDOTHELİAL CELL LOSS İN GRAVİTY GROUP İS SİGNİFİCANTLY HİGH AS COMPARED TO ACTİVE FLUİDİCS GROUP AND ENDOTHELİAL CELL LOSS PATİENTS OPERATED BY ACTİVE FLUİDİCS® SYSTEM İS FOUND TO BE 5% OR LESS. (P=0.002) KEYWORDS: CORNEA, ENDOTELİUM, PHACOEMULSİFİCATİON, ACTİVE FLUİDİCS, GRAVİTY, SPECULAR MİCROSCOPY