The effect of ramadan fasting on metabolic parametres in patients with tip 2 diabetes mellitus

To evaluate the effect of fasting on metabolic parameters patients with Type 2 Diabetes Mellitus. Between the months of July-August (pre-Ramadan) Sisli Etfal Education and Research Hospital Endocrine-Diabetes-Obesity Clinic which is monitored and is warned about fasting by a physician who insist on fasting 50 Type 2 diabetic patients (%26 males, %74 females) be consulted Diet and Nutrition Clinic, were studied prospectively. Type 1 DM, intensive insulin therapy in type 2 DM patients, pregnant patients with diabetes, patients with renal dysfunction were excluded. Before of the study gender, age, education level, height, weight, BMI (body-weight index), smoking, occupation, physical activity (> 150 m / w), duration of diabetes, a history of drug use, diabetic complications, comorbid diseases, history of acute metabolic coma were recorded, laboratory findings were reviewed. Medical nutrition therapy in these patients were adjusted for fasting. The mean age of patients was 51,10±8,95. The mean BMI of patients was 33,49±5,64 kg/m². Fasting blood glucose levels of patients before Ramadan was 124,36±42,57 mg/dL, after Ramadan it was 115,6±27,95 mg/dL. There was no significant change in fasting blood glucose levels ( p > 0.05). HbA1c levels of patients before Ramadan was 7,30±1,38, after Ramadan it was 6,80±0,72. In our study a significant decrease was detected in HbA1c levels ( p < 0.05 ). Total cholesterol levels of patients before Ramadan was 194,86±36,972 mg/dL, after Ramadan it was 191,08±39,611 mg/dL. There was no significant decrease in total cholesterol levels ( p > 0.05). Plasma triglyceride levels of patients before Ramadan was 184,16±142,450 mg/dL, after Ramadan it was 159,86±104,276 mg/dL. In our study a significant decrease was found in plasma triglyceride levels ( p < 0.05 ). HDL levels of patients before Ramadan was 44,98±10,387 mg/dL, after Ramadan it was 46,20±,11,254 mg/dL. There was no significant increase in HDL levels ( p > 0.05). LDL levels of patients before Ramadan was 114,07±28,5 mg/dL, after Ramadan it was 116,84±33,07 mg/dL. There was no significant change in LDL-cholesterol levels ( p > 0.05).